Prostemics is a leader
in exosome technology
Adipose-Derived Stem Cell Conditioned Media
Stem cell technologies for
ensuring skin cell regeneration
and prompt restoration

AAPE® is advanced adipose-derived stem cell conditioned media.
It contains hundreds of growth factors and proteins.
AAPE® maximizes the revitalizing effects of your skin and hair follicles
with its unique protein formula.

Chosen by
over 30 countries
Used by
3,000+ doctors

AAPE® is the first productbased on stem cell described in SCI journals
with clinical results in humans.

  • FDA Approval
    US FDA, CFDA approval, PCPC US registeration
  • SCI Journals
    More than 20 papers in SCI journals LEARN MORE
  • Patents
    28 Patents registered worldwide LEARN MORE
Stem cell technology for skin cell regeneration and restoration. AAPE® is a mixture of refined growth factors extracted from
human adipose-derived stem cell conditioned media. It induces
collagen synthesis in dermal cells to maximize the revitalizing
effects of the skin and hair follicles.
  • Human sources

    Biocompatible non-recombinant growth
    factors derived from human source ADSCs
    have minimal side effects

  • Natural composition

    Natural composition of the various growth
    factors derived from ADSCs can provide
    the best biological activity

  • Synergistic effect

    Each growth factor has pharmacological effects
    but combination of growth factors may enhance
    the pharmacological action of single protein

What are stem cells?

Stem cells are primal cells found in all multi-cellular organisms that retain the ability
to renew themselves through mitotic cell division and can differentiate into a wide range of specialized cell types.

Adipose-Derived Stem Cell (ADSC)

Human adipocytes extracted during the process of lipoaspiration contain the maximum number of stem cells in the human body.

AAPE® is

the global standard of skin·hair anti-aging solution

  • AAPE introduced in Textbook of Aging
    Skin (2010.USA)
    - Chapter20. 'Adipose - derived Stem
    cells and their Secretory Factors for
    Skin Aging’ p.201~212

  • Prostemics has serveral NDC codes

  • Approved by CTFA
    (currently PCPC) in Sep., 2006
    INCI: Human Adipocyte Conditioned Media
    Extract (21343)